Definition and meaning of nepotism: Nepotism is favoritism given to friends and family without regard to merit. It is a practice in which people in positions of power utilize their influence to help their family or friends gain access to resources and job opportunities, regardless of objective criteria. Nepotism has been a long-standing issue in American politics, as many elected officials use their status to appoint family members and friends to positions of power and influence regardless of their qualifications.